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Microsynth celebrates the company’s 30th anniversary with its staff.

Microsynth prepares for the future. Fortunately, Denise Schmidheini always thinks far into the future and so the headquarter building can be extended by two further floors.


Microsynth starts with contract manufacturing of antisense oligonucleotides for drug discovery. 


First clinical research studies under ICH guidelines are outsourced to Microsynth. 


To combine the knowledge built in the different departments and to use it for larger and more complex projects the contract research and outsoucing department is officially launched.


After 25 years at the forefront of the company, Denise and Tobias Schmidheini decide to step back and to hand over the operational management to two longstanding and deserved employees. Christof Wunderlin and Markus Schmid have committed themselves to advance the internationalization and further growth of the company but not neglecting the golden rule of Microsynth doing business in a sustainable and socially responsible way.


Microsynth merges with Seqlab GmbH in Göttingen to gain better access to the German life science market. Both companies bring together 40 years of experience in the area of DNA sequencing and establish the fastest overnight Sanger sequencing service in Germany. In contrast to its main competitors, an environmentally-friendly courier system (with trains instead of planes as predominant transport vehicles) delivers the samples to the lab in Göttingen.


Microsynth establishes a subsidiary in Vienna, Austria, to grow its market outside of Switzerland. Main focus of Microsynth Austria is to provide fast, on-site & green Sanger DNA sequencing services to its customers. Since its beginning in April 2012, the company is housed in a modern industrial building the heart of Vienna and run by Dr. Lukas Hartl and Bernhard Binishofer.


Ecogenics GmbH, a company specialized in microsatellite markers and genotyping becomes a part of Microsynth.


Since customers have all kind of different matrices where it is not always easy to isolate high-quality DNA respectively RNA, Microsynth starts its own DNA/RNA isolation department. That is much more convenient for the customer and we do control a larger part of the process which makes it more robust.


Next Generation Sequencing is the next big thing and Microsynth wants to be part of it. An NGS lab is established at our premises in Balgach.


Microsynth needs more space and so, in addition to the current building, a further 2000 sqm of laboratory and office space is being built.

But also in the oligonucleotide synthesis department something is happening. For the first time, RNA oligonucleotides are being synthesized.


Microsynth, constantly growing, is establishing qPCR and genotyping labs.


The company moves to its own premises in Balgach the hometown of Tobias.


Microsynth enters the market of Sanger sequencing. Denise and Tobias Schmidheini quickly noticed that besides the oligonucleotides there is also a need for fast Sanger sequencing.


The "laboratory" moves to Windisch, Aargau. Tobias Schmidheini at the self-made bench.


Denise and Tobias Schmidheini founded Microsynth as a "garage startup" when Tobias was still studying for his PhD at ETH Zurich. When producing oligonucleotides from 5 to 7 a.m. and from 7 to 11 p.m. out of Tobias' single room student accommodation (while simultaneously working at his PhD) he was overcoming a critical bottleneck at that time: Swiss academic institutes and local pharmaceutical industry had to wait up to 3 months for oligonucleotides since DNA synthesizers were limited and ran only from time to time for cost reasons.