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Veuillez trouver ci-dessous une sélection d'articles scientifiques évalués par des pairs dans lesquels le département de séquençage de nouvelle génération de Microsynth a été impliqué.

Séquençage Ciblé

Métagénomique des Amplicons
  • Pushkareva E, Elster J, Kudoh S, Imura S and Becker B (2024) Microbial community composition of terrestrial habitats in East Antarctica with a focus on microphototrophs. Front. Microbiol. 14:1323148. doi: 10.3389/fmicb.2023.1323148
  • Mariana Erthal rocha, Norberto Mangiavacchi, Marcia Marques et al. Succession from acetoclastic to hydrogenotrophic microbial community during sewage sludge anaerobic digestion for bioenergy production, 05 January 2024, PREPRINT (Version 1) available at Research Square []
  • Matthias T. BuhmannDominik AbtOliver NolteThomas R. NeuSebastian StrempelWerner C. AlbrichPatrick BetschartValentin ZumsteinAntonia NeelsKatharina Maniura-Weber, Qun Ren (2019) Encrustations on ureteral stents from patients without urinary tract infection reveal distinct urotypes and a low bacterial load. Microbiome 7:60,
  • Petri RM, Pourazad P, Khiaosa-ard R, Klevenhusen F, Metzler-Zebeli BU, Zebeli Q (2017) Temporal dynamics of in-situ fiber-adherent bacterial community under ruminal acidotic conditions determined by 16S rRNA gene profiling. PLoS ONE 12(8): e0182271.
  • Schären, M. et al., Differential effects of monensin and a blend of essential oils on rumen microbiota composition of transition dairy cows, Journal of Dairy Science , Volume 100 , Issue 4 , 2765 - 2783
  • Schären M, Kiri K, Riede S, Gardener M, Meyer U, Hummel J, Urich T, Breves G and Dänicke S (2017) Alterations in the Rumen Liquid-, Particle- and Epithelium-Associated Microbiota of Dairy Cows during the Transition from a Silage- and Concentrate-Based Ration to Pasture in Spring.
    Front. Microbiol. 8:744. doi: 10.3389/fmicb.2017.00744
  • Wilkins, L. G. E. et al. Increased diversity of egg-associated bacteria on brown trout (Salmo trutta) at elevated temperatures. Sci. Rep. 5, 17084; doi: 10.1038/srep17084 (2015).
  • Cross, B. C. S. et al. Increasing the performance of pooled CRISPR–Cas9 drop-out screening. Sci. Rep. 6, 31782; doi: 10.1038/srep31782 (2016).
  • Ulrike Mock, Rafał Machowicz, Ilona Hauber, Stefan Horn, Pierre Abramowski, Belinda Berdien, Joachim Hauber, Boris Fehse; mRNA transfection of a novel TAL effector nuclease (TALEN) facilitates efficient knockout of HIV co-receptor CCR5, Nucleic Acids Research, Volume 43, Issue 11, 23 June 2015, Pages 5560–5571,
ChIP Seq
  • Sunny, D.E., Hammer, E., Strempel, S. et al. Nup133 and ERα mediate the differential effects of hyperoxia-induced damage in male and female OPCs. Mol Cell Pediatr 7, 10 (2020).

Séquençage des Transcriptomes

Transcriptome de Référence
  • Neves, R.C., Guimaraes, J.C., Strempel, S. et al., Transcriptome profiling of Symbion pandora (phylum Cycliophora): insights from a differential gene expression analysis, Org Divers Evol (2017) 17: 111.


  • Sandrine Borgeaud, Lisa C. Metzger, Tiziana Scrignari, Melanie Blokesch, The type VI secretion system of Vibrio cholerae fosters horizontal gene transfer, Science 02 Jan 2015: Vol. 347, Issue 6217, pp. 63-67. DOI: 10.1126/science.1260064
Petits ARN Seq


  • Boubaker G, Strempel S, Hemphill A, Müller N, Wang J, Gottstein B, et al. (2020) Regulation of hepatic microRNAs in response to early stage Echinococcus multilocularis egg infection in C57BL/6 mice. PLoS Negl Trop Dis 14(5): e0007640.
  • Bhupesh K. Prusty, Nitish Gulve, Suvagata Roy Chowdhury, Michael Schuster, Sebastian Strempel, Vincent Descamps, Thomas Rudel (2018) HHV-6 encoded small non-coding RNAs define an intermediate and early stage in viral reactivation, npj Genomic Medicine 3:25,

Genome Sequencing

  • Noémie Matthey, Sandrine Stutzmann, Candice Stoudmann, Nicolas Guex, Christian Iseli, Melanie Blokesch (2019) Neighbor predation linked to natural competence fosters the transfer of large genomic regions in Vibrio cholerae. eLife 8:e48212 DOI: 10.7554/eLife.48212
  • Grass, R. N., Heckel, R., Puddu, M., Paunescu, D. and Stark, W. J. (2015), Robust Chemical Preservation of Digital Information on DNA in Silica with Error-Correcting Codes. Angew. Chem. Int. Ed., 54: 2552–2555. doi:10.1002/anie.201411378