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LNA modification available

Locked Nucleic Acid (LNA) is a synthetic nucleic acid analogue containing a bridged, bicyclic sugar moiety. LNA fully complies with Watson- Crick base pairing rules. LNA:DNA hybrids show strongly improved annealing temperatures compared to their DNA:DNA counterparts. Therefore, the major advantage of LNA lies in the design options for primers and probes as the Tm can be finetuned to the needs of the oligonucleotide.

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The LNA can be chosen as a modification on our webshop.